Clinical Approach to Ocular Allergy
Epidemiology, Impact, and When to Treat
Allergic conjunctivitis is one of the most common external eye complaints seen in primary eye care. Symptoms of itching, tearing, redness, and eyelid swelling reduce visual comfort and productivity, especially during peak pollen seasons. Treatment should be escalated when lifestyle adjustments and artificial tears no longer control symptoms, when patients wear contact lenses that exacerbate inflammation, or when chronic exposure risks lid and surface changes such as papillary hypertrophy.
Antihistamines vs Mast Cell Stabilizers
Topical antihistamines provide rapid relief by blocking H1 receptors and reducing itch and redness within minutes. Mast cell stabilizers prevent degranulation and are most effective when started before allergen exposure or used continuously through the season. Many modern products combine both actions, delivering quick onset and sustained control in a single bottle. Understanding onset time, dosing frequency, and preservative load helps match the drug to the patient's symptom pattern and sensitivity.
Dual Action Agents and Short Courses of Steroids
Dual action drops such as olopatadine, ketotifen, bepotastine, and alcaftadine simplify regimens and improve adherence. For severe flares, a short course of a soft steroid or loteprednol formulation can break the inflammatory cycle. Steroids require careful follow up to monitor intraocular pressure, rule out herpetic disease, and taper appropriately to avoid rebound. Consider preservative free or low BAK options for patients with significant surface disease or heavy drop burden.
Patient Selection, Counseling, and Adjunctive Measures
Evaluate symptom severity, frequency, age, pregnancy status, systemic allergy history, and contact lens wear to pick the safest and most effective option. Teach proper instillation, spacing from contact lens insertion, and realistic expectations for onset and duration. Reinforce allergen avoidance, cold compresses, lubricants for dilution, and oral antihistamines when ocular and nasal symptoms coexist. Schedule follow up for persistent cases to confirm response and modify therapy if papillary or vernal disease is suspected.