Oral Medications in Eye Care

Oral Medications Overview

Pharmaceutical Management with Ophthalmic Orals

Oral medications play a significant role in the management of various eye conditions when topical treatments are insufficient or impractical. Optometrists may prescribe oral agents for a range of ocular diseases, including severe uveitis, ocular herpes, and certain forms of glaucoma, where systemic treatment is necessary to achieve therapeutic effects. These medications are essential for providing comprehensive care, particularly in cases where localized treatment alone cannot adequately address the condition.

Commonly used oral medications in ocular therapy include antibiotics, antiviral drugs, and carbonic anhydrase inhibitors. Oral antibiotics, such as doxycycline and azithromycin, are often prescribed for their broad-spectrum anti-infective properties, effectively treating bacterial infections that affect the eye and surrounding tissues. Antiviral drugs like acyclovir and valacyclovir are crucial for managing viral infections such as ocular herpes, reducing viral replication and mitigating symptoms.

For conditions like glaucoma, where intraocular pressure needs to be controlled systemically, oral carbonic anhydrase inhibitors, such as acetazolamide, are utilized to decrease aqueous humor production and lower intraocular pressure. These medications are particularly useful in acute situations or when patients are unresponsive to topical treatments.

Understanding the indications, mechanisms of action, and potential side effects of oral medications is vital for optometrists and eye care professionals. This knowledge ensures that they can effectively integrate oral medications into treatment plans, providing optimal care and improving patient outcomes. By leveraging the systemic effects of oral medications, eye care providers can address complex ocular conditions comprehensively and enhance the overall quality of vision care.

Oral Medications Table

BrandGenericDosingAmountAgesPregnancyMechanism
Amoxil
GenericPO
amoxicillin500mg po bid-tid x10d250/500/875mg>3 monthsBpenicillin
Augmentin
GenericPO
amoxicillin
clavulanate
250-500mg po bid-tid x10d250/500/875mg>3 monthsBpenicillin
β-lactamase inhibitor
Diamox
GenericPO
acetazolamide500mg po bid125/250mg
500mg ('Sequels')
>12 yearsCcarbonic anhydrase inhibitor
↓ aqueous production
Diclocil
GenericPO
dicloxacillin250mg po qid250/500mg>3 monthsBpenicillin
Famvir
GenericPO
famciclovir250mg po tid x 7d (simplex)
500mg po tid x 7d (zoster)
125/250/500mgNABguanine analogue
Keflex
GenericPO
cephalexin1-4g/d po250/500/750mg>1 yearBcephalosporin
Tylenol #3
GenericPO
acetaminophen 300mg
codeine 30mg
q4-6hsingle tablet>18 yearsCanalgesic
narcotic (Sch.III)
Ultracet
GenericPO
acetaminophen 325mg
tramadol 37.5mg
q4-6h
(max 8 tabs/d)
single tablet>12 yearsCanalgesic
narcotic (Sch.IV)
Ultram
GenericPO
tramadol hydrochlorideq4-6h
(max 400mg/d)
50mg>18 yearsCnarcotic (Sch.IV)
Valtrex
GenericPO
valcyclovir500mg po tid (simplex)
1g po tid x7d (zoster)
500mg/1g>12 yearsBguanine analogue
Vibramycin
GenericPO
doxycycline100mg po bid x7d50/100mg>8 yearsDtetracycline
Vicodin
GenericPO
acetaminophen 300mg
hydrocodone 5mg
q4-6h
(max 12 tabs/d)
single tabletNACnarcotic (Sch.II)
Z-Pak
GenericPO
azithromycinbid po x1d, then qd po x4d250mg x6
250/500/600mg
>6 monthsBmacrolide
Zovirax
GenericPO
acyclovir400mg po 5x/d x7d (simplex)
800mg po 5x/d x7d (zoster)
200/400/800mg>2 yearsBinhibits DNA polymerase